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Propofol suppresses cell viability, cell cycle progression and motility and induces cell apoptosis of ovarian cancer cells through suppressing MEK/ERK signaling via targeting circVPS13C/miR-145 axis

Abstract Background Propofol is a kind of common intravenous anaesthetic agent that plays an anti-tumor role in a variety of cancers, including ovarian cancer. However, the working mechanism of Propofol in ovarian cancer needs further exploration. Methods The viability and metastasis of ovarian canc...

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Principais autores: Huan Lu, Guanlin Zheng, Xiang Gao, Chanjuan Chen, Min Zhou, Longxin Zhang
格式: Artigo
语言:Inglês
出版: BMC 2021-02-01
丛编:Journal of Ovarian Research
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在线阅读:https://doi.org/10.1186/s13048-021-00775-3
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