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A cleavable peptide adapter augments the activity of targeted toxins in combination with the glycosidic endosomal escape enhancer SO1861

Abstract Background Treatment with tumor-targeted toxins attempts to overcome the disadvantages of conventional cancer therapies by directing a drug’s cytotoxic effect specifically towards cancer cells. However, success with targeted toxins has been hampered as the constructs commonly remain bound t...

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Príomhchruthaitheoirí: Finn J. Schulze, Mazdak Asadian-Birjand, Michael Pradela, Nicole Niesler, Gregor Nagel, Hendrik Fuchs
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2024-04-01
Sraith:BMC Biotechnology
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12896-024-00854-5
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