Hypomethylation-mediated upregulation of the WASF2 promoter region correlates with poor clinical outcomes in hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) is one of the most common and lethal cancers worldwide. Wiskott–Aldrich syndrome protein family member 2 (WASF2) is an integral member of the actin cytoskeleton pathway, which plays a crucial role in cell motility. In this study, we aimed to explore...

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Główni autorzy:	Hye Ri Ahn, Geum Ok Baek, Moon Gyeong Yoon, Ju A Son, Jung Hwan Yoon, Jae Youn Cheong, Hyo Jung Cho, Ho Chul Kang, Jung Woo Eun, Soon Sun Kim
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2022-04-01
Seria:	Journal of Experimental & Clinical Cancer Research
Hasła przedmiotowe:	Carcinogenesis Liver neoplasms DNA methylation Prognosis WASF2
Dostęp online:	https://doi.org/10.1186/s13046-022-02365-7
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