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Hypomethylation-mediated upregulation of the WASF2 promoter region correlates with poor clinical outcomes in hepatocellular carcinoma

Abstract Background Hepatocellular carcinoma (HCC) is one of the most common and lethal cancers worldwide. Wiskott–Aldrich syndrome protein family member 2 (WASF2) is an integral member of the actin cytoskeleton pathway, which plays a crucial role in cell motility. In this study, we aimed to explore...

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Principais autores: Hye Ri Ahn, Geum Ok Baek, Moon Gyeong Yoon, Ju A Son, Jung Hwan Yoon, Jae Youn Cheong, Hyo Jung Cho, Ho Chul Kang, Jung Woo Eun, Soon Sun Kim
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-04-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
Carcinogenesis
Liver neoplasms
DNA methylation
Prognosis
WASF2
Online adgang:https://doi.org/10.1186/s13046-022-02365-7
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