The influence of psychosocial stress on functional connectivity and neuroendocrine markers in adolescents with depressive and comorbid anxiety disorders: a study protocol

Abstract Background Psychosocial stress is a major risk factor for adolescent depression and anxiety, impacting neurodevelopment through hypothalamic-pituitary-adrenal axis and oxytocinergic system dysregulation. Stress-related alterations in fronto-limbic resting-state functional connectivity (rsFC...

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Detalhes bibliográficos

Principais autores:	Ricarda Jacob, Alexandra Otto, Irina Jarvers, Stephanie Kandsperger, Angelika Ecker, Daniel Schleicher, Wilhelm M. Malloni, Inga D. Neumann, Romuald Brunner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
coleção:	BMC Psychiatry
Assuntos:	Adolescence Major depressive disorder Anxiety disorders Functional connectivity Oxytocin Cortisol
Acesso em linha:	https://doi.org/10.1186/s12888-025-07689-0
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