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The influence of psychosocial stress on functional connectivity and neuroendocrine markers in adolescents with depressive and comorbid anxiety disorders: a study protocol

Abstract Background Psychosocial stress is a major risk factor for adolescent depression and anxiety, impacting neurodevelopment through hypothalamic-pituitary-adrenal axis and oxytocinergic system dysregulation. Stress-related alterations in fronto-limbic resting-state functional connectivity (rsFC...

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Principais autores: Ricarda Jacob, Alexandra Otto, Irina Jarvers, Stephanie Kandsperger, Angelika Ecker, Daniel Schleicher, Wilhelm M. Malloni, Inga D. Neumann, Romuald Brunner
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:BMC Psychiatry
Fag:
Online adgang:https://doi.org/10.1186/s12888-025-07689-0
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