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Assessing the role of evolutionary information for enhancing protein language model embeddings

Abstract Embeddings from protein Language Models (pLMs) are replacing evolutionary information from multiple sequence alignments (MSAs) as the most successful input for protein prediction. Is this because embeddings capture evolutionary information? We tested various approaches to explicitly incorpo...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Kyra Erckert, Burkhard Rost
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2024-09-01
Rangatū:Scientific Reports
Ngā marau:
Urunga tuihono:https://doi.org/10.1038/s41598-024-71783-8
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