Integrating cells, scaffolds, and molecular regulation: a mechanobiological and translational review of bioengineering therapies for intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is a primary cause of chronic low back pain, severely impacting patients' quality of life. Conventional treatments focus on symptom relief but fail to restore disc structure and function. Recent bioengineering advances offer regenerative solutions, integrating...

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Autori principali:	Wang Hao, Chen Renchang, Xia Wa, Huang Wenhao, Zhou Bingqian, Zheng Xiqiu, Wang Jiahao, Wu Yadong, Li Nianhu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-04-01
Serie:	Frontiers in Bioengineering and Biotechnology
Soggetti:	bioengineering biomaterials cell therapy gene therapy intervertebral disc degeneration mechanobiology
Accesso online:	https://www.frontiersin.org/articles/10.3389/fbioe.2026.1803183/full
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