Integrating cells, scaffolds, and molecular regulation: a mechanobiological and translational review of bioengineering therapies for intervertebral disc degeneration

Intervertebral disc degeneration (IDD) is a primary cause of chronic low back pain, severely impacting patients' quality of life. Conventional treatments focus on symptom relief but fail to restore disc structure and function. Recent bioengineering advances offer regenerative solutions, integrating...

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Detalles Bibliográficos

Principais autores:	Wang Hao, Chen Renchang, Xia Wa, Huang Wenhao, Zhou Bingqian, Zheng Xiqiu, Wang Jiahao, Wu Yadong, Li Nianhu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2026-04-01
Series:	Frontiers in Bioengineering and Biotechnology
Assuntos:	bioengineering biomaterials cell therapy gene therapy intervertebral disc degeneration mechanobiology
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fbioe.2026.1803183/full
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