Influence of Gender, Body Mass Index, and Age on the Pharmacokinetics of Itraconazole in Healthy Subjects: Non-Compartmental Versus Compartmental Analysis

Itraconazole is a triazole antifungal agent with highly variable pharmacokinetics, with not yet fully identified factors as the source of this variability. Our study aimed to examine the influence of body mass index, gender, and age on the first dose pharmacokinetics of itraconazole in healthy subje...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Milijana N. Miljković, Nemanja Rančić, Aleksandra Kovačević, Bojana Cikota-Aleksić, Ivan Skadrić, Vesna Jaćević, Momir Mikov, Viktorija Dragojević-Simić
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-06-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	itraconazole hydroxy-itraconazole gender non-compartmental analysis compartmental analysis genetic polymorphism
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fphar.2022.796336/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!