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DNA Cleavage and Cytotoxic Activity of Copper(II) Complexes Based on Reduced Schiff Bases Derived From Salicylaldehyde and Amino Acids

Metal complexes, which, under physiologic conditions, show redox properties and are able to bind to DNA, are great tools to cleave the DNA chain. This aspect is of great importance for their use as antineoplastic drugs. We synthesized ligands derived from short-chain amino acids and from salicylalde...

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Bibliografski detalji
Glavni autori: Korcová Jana, Húserková Mária, Lintnerová Lucia, Valentová Jindra
Format: Artigo
Jezik:Inglês
Izdano: Sciendo 2024-03-01
Serija:European Pharmaceutical Journal
Teme:
Online pristup:https://doi.org/10.2478/afpuc-2024-0003
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