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DNA Cleavage and Cytotoxic Activity of Copper(II) Complexes Based on Reduced Schiff Bases Derived From Salicylaldehyde and Amino Acids

Metal complexes, which, under physiologic conditions, show redox properties and are able to bind to DNA, are great tools to cleave the DNA chain. This aspect is of great importance for their use as antineoplastic drugs. We synthesized ligands derived from short-chain amino acids and from salicylalde...

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Principais autores: Korcová Jana, Húserková Mária, Lintnerová Lucia, Valentová Jindra
Formato: Artigo
Idioma:Inglês
Publicado em: Sciendo 2024-03-01
coleção:European Pharmaceutical Journal
Assuntos:
Acesso em linha:https://doi.org/10.2478/afpuc-2024-0003
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