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SOCS1 expression in cancer cells: potential roles in promoting antitumor immunity

Suppressor of cytokine signaling 1 (SOCS1) is a potent regulator immune cell responses and a proven tumor suppressor. Inhibition of SOCS1 in T cells can boost antitumor immunity, whereas its loss in tumor cells increases tumor aggressivity. Investigations into the tumor suppression mechanisms so far...

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Bibliografische gegevens
Hoofdauteurs: Subburaj Ilangumaran, Yirui Gui, Akhil Shukla, Sheela Ramanathan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2024-02-01
Reeks:Frontiers in Immunology
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Online toegang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1362224/full
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