Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice

BackgroundAlthough activation of inflammatory processes is essential to fight infections, its prolonged impact on brain function is well known to contribute to the pathophysiology of many medical conditions, including neuropsychiatric disorders. Therefore, identifying novel strategies to selectively...

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Главные авторы:	Camille Monchaux de Oliveira, Jennifer Morael, Alexandrine Guille, Camille Amadieu, Sylvie Vancassel, David Gaudout, Lucile Capuron, Line Pourtau, Nathalie Castanon
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-10-01
Серии:	Frontiers in Nutrition
Предметы:	nutritional interventions saffron extract neuroinflammation lipopolysaccharide sickness behavior kynurenine pathway
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fnut.2023.1267839/full
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