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Brain Kynurenine and BH4 Pathways: Relevance to the Pathophysiology and Treatment of Inflammation-Driven Depressive Symptoms

The prevalence of depressive disorders is growing worldwide, notably due to stagnation in the development of drugs with greater antidepressant efficacy, the continuous large proportion of patients who do not respond to conventional antidepressants, and the increasing rate of chronic medical conditio...

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Principais autores: Sylvie Vancassel, Lucile Capuron, Nathalie Castanon
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neuroscience
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Acceso en liña:https://www.frontiersin.org/article/10.3389/fnins.2018.00499/full
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