Insightful chemistry of molecular docking studies and ADMET profiling of 4-amino-1,2,4-triazole scaffolds as potential inhibitor of DprE1 enzymes as antitubercular agents

Abstract Background Airborne transmission of the bacterial illness tuberculosis (TB) is attributed to Mycobacterium tuberculosis (Mtb). Mycobacterium tuberculosis, a multidrug-resistant strain, spreads quickly and is the cause of multidrug-resistant tuberculosis (MDRTB). A study was conducted to inv...

全面介紹

書目詳細資料

Principais autores:	Santosh Prasad Chaudhary Kurmi, Dipanjan Karati
格式:	Artigo
語言:	Inglês
出版:	Springer 2025-06-01
叢編:	Discover Chemistry
主題:	DprE1 enzyme Tuberculosis Toxicity prediction Retrobiocat route Bioactivity radar analysis
在線閱讀:	https://doi.org/10.1007/s44371-025-00208-w
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!