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Insightful chemistry of molecular docking studies and ADMET profiling of 4-amino-1,2,4-triazole scaffolds as potential inhibitor of DprE1 enzymes as antitubercular agents

Abstract Background Airborne transmission of the bacterial illness tuberculosis (TB) is attributed to Mycobacterium tuberculosis (Mtb). Mycobacterium tuberculosis, a multidrug-resistant strain, spreads quickly and is the cause of multidrug-resistant tuberculosis (MDRTB). A study was conducted to inv...

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Auteurs principaux: Santosh Prasad Chaudhary Kurmi, Dipanjan Karati
Format: Artigo
Langue:Inglês
Publié: Springer 2025-06-01
Collection:Discover Chemistry
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Accès en ligne:https://doi.org/10.1007/s44371-025-00208-w
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