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Paralogs of the Calcium-Dependent Activator Protein for Secretion Differentially Regulate Synaptic Transmission and Peptide Secretion in Sensory Neurons

The two paralogs of the calcium-dependent activator protein for secretion (CAPS) are priming factors for synaptic vesicles (SVs) and neuropeptide containing large dense-core vesicles (LDCVs). Yet, it is unclear whether CAPS1 and CAPS2 regulate exocytosis of these two vesicle types differentially in...

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Principais autores: Ali H. Shaib, Angelina Staudt, Ali Harb, Margarete Klose, Ahmed Shaaban, Claudia Schirra, Ralf Mohrmann, Jens Rettig, Ute Becherer
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-09-01
coleção:Frontiers in Cellular Neuroscience
Assuntos:
DRG neurons
CADPS
exocytosis
priming
large dense core vesicle
synaptic transmission
Acesso em linha:https://www.frontiersin.org/article/10.3389/fncel.2018.00304/full
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