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Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis

Exocytosis of secretory vesicles requires the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins and small GTPase Rabs. As a Rab3/Rab27 effector protein on secretory vesicles, Rabphilin 3A was implicated to interact with SNAP-25 to regulate vesicle exocytosis in n...

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Autors principals: Tianzhi Li, Qiqi Cheng, Shen Wang, Cong Ma
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2022-09-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/79926
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