Longitudinal assessment of cognitive decline and resilience in high-level Alzheimer disease neuropathologic change

Abstract Background Alzheimer disease neuropathologic change (ADNC) is the most common pathology underlying cognitive impairment and dementia in the aging population, but there is significant variation in outcome between affected individuals. Moreover, other common neurodegenerative processes are of...

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Detalhes bibliográficos

Principais autores:	Timothy E. Richardson, Shrishtee Kandoi, Francisco C. Almeida, Susan K. Rohde, Gabriel A. Marx, Leyla Canbeldek, Satomi Hiya, Carolina Maldonado-Díaz, Jorge Samanamud, Kevin Clare, Cheyanne C. Slocum, Lakshmi Shree Kulumani Mahadevan, Lily Yu-Chia Chiu, Kurt Farrell, John F. Crary, Elena V. Daoud, Charles L. White, Sara E. Espinoza, Mitzi M. Gonzales, Tiago Gil Oliveira, Jamie M. Walker
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
Colecção:	Alzheimer’s Research & Therapy
Assuntos:	Alzheimer disease neuropathologic change (ADNC) Resilience Resistance Limbic-predominant age-related TDP-43 encephalopathy (LATE) Cognitive trajectory Braak stage
Acesso em linha:	https://doi.org/10.1186/s13195-025-01904-6
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