The Multifaceted Role of Growth Differentiation Factor 15 (GDF15): A Narrative Review from Cancer Cachexia to Target Therapy

<b>Background: </b>Growth Differentiation Factor 15 (GDF15) has emerged as a key biomarker and therapeutic target in oncology, with roles extending beyond cancer cachexia. Elevated GDF15 levels correlate with poor prognosis across several solid tumors, including colorectal, gastric, pancreatic, brea...

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Egile Nagusiak:	Daria Maria Filippini, Donatella Romaniello, Francesca Carosi, Laura Fabbri, Andrea Carlini, Raffaele Giusti, Massimo Di Maio, Salvatore Alfieri, Mattia Lauriola, Maria Abbondanza Pantaleo, Lorena Arribas, Marc Oliva, Paolo Bossi, Laura Deborah Locati
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2025-08-01
Saila:	Biomedicines
Gaiak:	GDF15 cancer biomarker GFRAL chemotherapy resistance head and neck cancer cachexia
Sarrera elektronikoa:	https://www.mdpi.com/2227-9059/13/8/1931
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