Binary combinatorial scanning reveals potent poly-alanine-substituted inhibitors of protein-protein interactions
Alanine substitution in peptides is crucial for studying peptide-based inhibitors of protein–protein interactions, but limited information is obtained from single alanine substitution. Here, the authors develop a label-free combinatorial alanine affinity selection platform to establish multi-alanine...
Furkejuvvon:
| Váldodahkkit: | , , , , , , , |
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| Materiálatiipa: | Artigo |
| Giella: | Inglês |
| Almmustuhtton: |
Nature Portfolio
2022-10-01
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| Ráidu: | Communications Chemistry |
| Liŋkkat: | https://doi.org/10.1038/s42004-022-00737-w |
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