Binary combinatorial scanning reveals potent poly-alanine-substituted inhibitors of protein-protein interactions
Alanine substitution in peptides is crucial for studying peptide-based inhibitors of protein–protein interactions, but limited information is obtained from single alanine substitution. Here, the authors develop a label-free combinatorial alanine affinity selection platform to establish multi-alanine...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Portfolio
2022-10-01
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| سلاسل: | Communications Chemistry |
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s42004-022-00737-w |
| الوسوم: |
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