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Quantifying negative selection on synonymous variants

Summary: Widespread adoption of DNA sequencing has resulted in large numbers of genetic variants, whose contribution to disease is not easily determined. Although many types of variation are known to disrupt cellular processes in predictable ways, for some categories of variants, the effects may not...

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Principais autores: Mikhail Gudkov, Loïc Thibaut, Eleni Giannoulatou
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2024-04-01
סדרה:HGG Advances
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גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2666247724000010
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