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Iron accumulation in hypothalamus promotes age-dependent obesity and metabolic dysfunction of male mice

Abstract With the progression of aging, age-dependent obesity and metabolic disorders have garnered increasing attention, yet their underlying mechanisms remain poorly understood. Dysregulation of iron homeostasis is strongly linked to aging; however, its role in age-dependent obesity remains unclea...

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Main Authors: Xinyu Wang, Xiaoyue Xiong, Ye Xuan, Wen Tian, Liwei Chen, Zhuo Chen, Yi Zhang, Wei L. Shen, Cheng Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2025-10-01
Colecção:Molecular Biomedicine
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Acesso em linha:https://doi.org/10.1186/s43556-025-00324-0
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