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Aging alters the expression of trophic factors and tight junction proteins in the mouse choroid plexus

Abstract Background The choroid plexus (CP) is an understudied tissue in the central nervous system and is primarily implicated in cerebrospinal fluid (CSF) production. CP also produces numerous neurotrophic factors (NTF) which circulate to different brain regions. Regulation of NTFs in the CP durin...

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Principais autores: Jayanarayanan Sadanandan, Monica Sathyanesan, Samuel S. Newton
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-09-01
Serier:Fluids and Barriers of the CNS
Fag:
Choroid plexus
Blood–cerebrospinal fluid barrier
Tight junctional proteins
Neurotrophic factors
Aging
Epithelial cells
Online adgang:https://doi.org/10.1186/s12987-024-00574-0
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