Dysregulation of baseline and learning-dependent protein degradation in the aged hippocampus

The ubiquitin-proteasome system (UPS) controls the majority of protein degradation in cells and dysregulation of the UPS has been implicated in the pathophysiology of numerous neurodegenerative disorders, including Alzheimer’s disease. Further, strong evidence supports a critical role for the UPS in...

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Hlavní autoři:	Morgan B. Patrick, Natalie J. Preveza, Shannon E. Kincaid, Gueladouan Setenet, Jennifer R. Abraham, Adam Cummings, Shifa Banani, W. Keith Ray, Richard F. Helm, Sydney Trask, Timothy J. Jarome
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-09-01
Edice:	Brain Research Bulletin
Témata:	Aging Memory Hippocampus Ubiquitin Proteasome Retrosplenial Cortex
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0361923024001485
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