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Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond

Given the multiple differences between mice and men, it was once thought that mice could not be used to model atherosclerosis, principally a human disease. Apolipoprotein E-deficient (apoEKO) mice have convincingly changed this view, and the ability to model human-like plaques in these mice has prov...

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Bibliografiske detaljer
Principais autores: Avani A. Pendse, Jose M. Arbones-Mainar, Lance A. Johnson, Michael K. Altenburg, Nobuyo Maeda
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2009-01-01
Serier:Journal of Lipid Research
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Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520306088
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