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Anti-tau intrabodies: From anti-tau immunoglobulins to the development of functional scFv intrabodies

Over the last decade, there has been a growing interest in intrabodies and their therapeutic potential. Intrabodies are antibody fragments that are expressed inside a cell to target intracellular antigens. In the context of intracellular protein misfolding and aggregation, such as tau pathology in A...

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Autori principali: Dina Rodrigues Martins, Fern Sha, Wim Van der Elst, Pei-Yu Shih, Jens Devoght, Kristof Van Kolen, Marc Mercken, Bianca Van Broeck, Paul Declerck, Clara Theunis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2023-12-01
Serie:Molecular Therapy: Methods & Clinical Development
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2329050123001973
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