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The improvement of anti-HER2 scFv soluble expression in Escherichia coli

The relationship between the expression of HER2 and malignity of breast tumors has led to the generation of antibodies targeting HER2+ tumors. In addition, the expression of scFvs, as the smallest antigen-binding region of antibody containing two disulfide bonds in Escherichia coli often results in...

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Bibliografski detalji
Glavni autori: Farzaneh Farshdari, Maryam Ahmadzadeh, Leila Nematollahi, Elham Mohit
Format: Artigo
Jezik:Inglês
Izdano: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2020-03-01
Serija:Brazilian Journal of Pharmaceutical Sciences
Teme:
Online pristup:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100519&tlng=en
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