Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies

There has been an increased interest in pharmacokinetics and pharmacodynamics (PKPD) of anti-tuberculosis drugs. A better understanding of the relationship between drug exposure, antimicrobial kill and acquired drug resistance is essential not only to optimize current treatment regimens but also to...

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Bibliografische gegevens

Hoofdauteurs:	Jan-Willem C. Alffenaar, Jurriaan E. M. de Steenwinkel, Andreas H. Diacon, Ulrika S. H. Simonsson, Shashikant Srivastava, Sebastian G. Wicha
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Frontiers Media S.A. 2022-12-01
Reeks:	Frontiers in Pharmacology
Onderwerpen:	tuberculosis pharmacokinetics pharmacodynamics modeling and simulation dose optimization anti-TB drugs
Online toegang:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1063453/full
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