Pharmacokinetic and pharmacodynamic modeling of oral mitiglinide on glucose lowering in healthy Chinese volunteers

Abstract Background Mitiglinide is a widely used agent for diabetic treatment. We established a pharmacokinetic-pharmacodynamic (PK-PD) model to illustrate the relationship between mitiglinide plasma concentration and its glucose lowering effects in healthy volunteers. Methods The volunteers partici...

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Detalhes bibliográficos

Principais autores:	Shijia Liu, Peidong Chen, Yang Zhao, Guoliang Dai, Bingting Sun, Yao Wang, Anwei Ding, Wenzheng Ju
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2017-07-01
coleção:	BMC Pharmacology and Toxicology
Assuntos:	Mitiglinide Pharmacodynamic Pharmacokinetic Pharmacokinetic–pharmacodynamics modeling Plasma glucose
Acesso em linha:	http://link.springer.com/article/10.1186/s40360-017-0161-6
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