Recurrent evolution of ligand-binding domain multiplicity fine-tunes TGFβ signaling in vertebrates
Abstract From sponges to mammals, TGFβ signalling is a central regulator of body plan, cell fate and tissue homeostasis, with receptor architecture highly conserved across metazoans. Here we identify unexpected evolutionary divergence within a key receptor structure: 12 independent ligand-binding do...
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| Автори: | , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Portfolio
2026-05-01
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| Серія: | Nature Communications |
| Онлайн доступ: | https://doi.org/10.1038/s41467-026-73340-5 |
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