Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection

Engineered neutralizing antibodies are potential therapeutics for numerous viruses, such as respiratory syncytial virus (RSV). Here, the authors develop an mRNA-based approach to express membrane-anchored neutralizing antibodies in the lung and demonstrate that it inhibits RSV infections in mice.

מידע ביבליוגרפי

Principais autores:	Pooja Munnilal Tiwari, Daryll Vanover, Kevin E. Lindsay, Swapnil Subhash Bawage, Jonathan L. Kirschman, Sushma Bhosle, Aaron W. Lifland, Chiara Zurla, Philip J. Santangelo
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2018-10-01
סדרה:	Nature Communications
גישה מקוונת:	https://doi.org/10.1038/s41467-018-06508-3
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!