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Complement Properdin Determines Disease Activity in MRL/<i>lpr</i> Mice

<i>Background and objects:</i> In systemic lupus erythematosus, circulating immune complexes activate complement and, when trapped in renal capillaries, cause glomerulonephritis. Mouse models have been used in the preclinical assessment of targeting complement activation pathways to manage chronic i...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Hasanain Alaridhee, Azzah Alharbi, Zeayd Saeed, Róisín C. Thomas, Cordula M. Stover
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2020-08-01
Rangatū:Medicina
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1648-9144/56/9/430
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