Complement Properdin Determines Disease Activity in MRL/<i>lpr</i> Mice
<i>Background and objects:</i> In systemic lupus erythematosus, circulating immune complexes activate complement and, when trapped in renal capillaries, cause glomerulonephritis. Mouse models have been used in the preclinical assessment of targeting complement activation pathways to manage chronic i...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI AG
2020-08-01
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| シリーズ: | Medicina |
| 主題: | |
| オンライン･アクセス: | https://www.mdpi.com/1648-9144/56/9/430 |
| タグ: |
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