Regulation of Geldanamycin Biosynthesis by Cluster-Situated Transcription Factors and the Master Regulator PhoP

Geldanamycin and the closely related herbimycins A, B, and C are benzoquinone-type ansamycins with antitumoral activity. They are produced by <i>Streptomyces hygroscopicus</i> var. <i>geldanus</i>, <i>Streptomyces lydicus</i> and <i>Streptomyces autolyticus</i> among other <i>Streptomyces</i> strain...

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Principais autores:	Juan F. Martín, Angelina Ramos, Paloma Liras
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2019-06-01
coleção:	Antibiotics
Assuntos:	geldanamycins <i>Streptomyces hygroscopicus</i> antitumorals biosynthesis gene cluster phosphate control
Acesso em linha:	https://www.mdpi.com/2079-6382/8/3/87
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