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Staphylococcus aureus δ-toxin present on skin promotes the development of food allergy in a murine model

BackgroundPatients with food allergy often suffer from atopic dermatitis, in which Staphylococcus aureus colonization is frequently observed. Staphylococcus aureus δ-toxin activates mast cells and promotes T helper 2 type skin inflammation in the tape-stripped murine skin. However, the physiological...

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Principais autores: Hiromichi Yamada, Ayako Kaitani, Kumi Izawa, Tomoaki Ando, Anna Kamei, Shino Uchida, Akie Maehara, Mayuki Kojima, Risa Yamamoto, Hexing Wang, Masakazu Nagamine, Keiko Maeda, Koichiro Uchida, Nobuhiro Nakano, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu, Jiro Kitaura
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-05-01
Serier:Frontiers in Immunology
Fag:
food allergy
epicutaneous sensitization
murine model
IgE
Staphylococcus aureus δ-toxin
IL-1α
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1173069/full
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