Host adaptive mutations in the 2009 H1N1 pandemic influenza A virus PA gene regulate translation efficiency of viral mRNAs via GRSF1
A comparison between avian and human influenza A virus polymerases suggests that mutations in the PA subunit from 2009 pH1N1 enhanced cytosolic accumulation and translation of viral mRNA, in a manner dependent on the RNA binding protein, GRSF1.
Gardado en:
| Principais autores: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2022-10-01
|
| Series: | Communications Biology |
| Acceso en liña: | https://doi.org/10.1038/s42003-022-04082-5 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|