EPDR1 Links Fibroblast Dysfunction to Disease Severity in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by aberrant fibroblast activation, lysosomal dysfunction, and cellular senescence. Transcriptomic analyses have identified ependymin-related 1 (EPDR1) as a fibroblast-enriched gene in IPF, but its biological function rem...

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主要な著者:	Jong-Uk Lee, Seung-Lee Park, Min Kyung Kim, Eunjeong Seo, Hun-Gyu Hwang, Jung Hyun Kim, Hun Soo Chang, Choon-Sik Park
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2025-09-01
シリーズ:	Cells
主題:	EPDR1 idiopathic pulmonary fibrosis lysosome fibroblasts autophagy cellular senescence
オンライン･アクセス:	https://www.mdpi.com/2073-4409/14/19/1515
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