EPDR1 Links Fibroblast Dysfunction to Disease Severity in Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease characterized by aberrant fibroblast activation, lysosomal dysfunction, and cellular senescence. Transcriptomic analyses have identified ependymin-related 1 (EPDR1) as a fibroblast-enriched gene in IPF, but its biological function rem...

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Autori principali:	Jong-Uk Lee, Seung-Lee Park, Min Kyung Kim, Eunjeong Seo, Hun-Gyu Hwang, Jung Hyun Kim, Hun Soo Chang, Choon-Sik Park
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-09-01
Serie:	Cells
Soggetti:	EPDR1 idiopathic pulmonary fibrosis lysosome fibroblasts autophagy cellular senescence
Accesso online:	https://www.mdpi.com/2073-4409/14/19/1515
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