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Liposome encapsulated polydopamine nanoparticles: Enhancing ferroptosis and activating hypoxia prodrug activity

The short lifespan of active oxygen species and depressed O2 level during ferroptosis treatment in tumor cells weaken ferroptosis therapy. How to improve the utilization efficiency of active oxygen species generated in real time is pivotal for anticancer treatment. Herein, the tirapazamine (TPZ) loa...

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Автори: Yijun Guo, Huiling Luo, Hairong Jiang, Xinxin Liu, Xinrui Long, Yinuo Hou, Zhou Chen, Yanan Sun, Dongtao Ge, Wei Shi
Формат: Artigo
Мова:Inglês
Опубліковано: Elsevier 2024-04-01
Серія:Materials Today Bio
Предмети:
Ferroptosis
Lipid peroxidation
Unsaturated liposome
Hypoxic activation prodrug
Combination therapy
Онлайн доступ:http://www.sciencedirect.com/science/article/pii/S2590006424000681
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