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Adeno-Associated Virus (AAV) Gene Delivery: Dissecting Molecular Interactions upon Cell Entry

Human gene therapy has advanced from twentieth-century conception to twenty-first-century reality. The recombinant Adeno-Associated Virus (rAAV) is a major gene therapy vector. Research continues to improve rAAV safety and efficacy using a variety of AAV capsid modification strategies. Significant f...

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Principais autores: Edward E. Large, Mark A. Silveria, Grant M. Zane, Onellah Weerakoon, Michael S. Chapman
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-07-01
coleção:Viruses
Assuntos:
adeno-associated virus
AAV
gene therapy
virus structure
AAV receptor
AAV attachment factor
Acesso em linha:https://www.mdpi.com/1999-4915/13/7/1336
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