Large-Scale Expansion of Human Liver Stem Cells Using Two Different Bioreactor Systems

The assessment of human liver stem cells (HLSCs) as cell therapeutics requires scalable, controlled expansion processes. We first focused on defining appropriate process parameters for HLSC expansion such as seeding density, use of antibiotics, optimal cell age and critical metabolite concentrations...

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書誌詳細

主要な著者:	Jan Thorbow, Andrea Strauch, Viktoria Pfening, Jan-Philip Klee, Patricia Brücher, Björn Boshof, Florian Petry, Peter Czermak, Maria Beatriz Herrera Sanchez, Denise Salzig
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2024-07-01
シリーズ:	Bioengineering
主題:	stirred-tank bioreactor multi-plate bioreactor scale-up oxygen limitation <i>k<sub>L</sub>a</i> long-term cultivation
オンライン･アクセス:	https://www.mdpi.com/2306-5354/11/7/692
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