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Induction of subject-ventilator asynchrony by variation of respiratory parameters in a lung injury model in pigs

Abstract Background Subject-ventilator asynchrony (SVA) was shown to be associated with negative clinical outcomes. To elucidate pathophysiology pathways and effects of SVA on lung tissue histology a reproducible animal model of artificially induced asynchrony was developed and evaluated. Methods Al...

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Principais autores: Xi Ran, Martin Scharffenberg, Jakob Wittenstein, Mark Leidermann, Andreas Güldner, Thea Koch, Marcelo Gama de Abreu, Robert Huhle
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-10-01
Serier:Respiratory Research
Fag:
Subject-ventilator asynchrony
Ineffective efforts
Auto-triggering
Double-triggering
Large animal model
Online adgang:https://doi.org/10.1186/s12931-024-02984-y
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