Induction of subject-ventilator asynchrony by variation of respiratory parameters in a lung injury model in pigs

Abstract Background Subject-ventilator asynchrony (SVA) was shown to be associated with negative clinical outcomes. To elucidate pathophysiology pathways and effects of SVA on lung tissue histology a reproducible animal model of artificially induced asynchrony was developed and evaluated. Methods Al...

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Bibliografische Detailangaben

Hauptverfasser:	Xi Ran, Martin Scharffenberg, Jakob Wittenstein, Mark Leidermann, Andreas Güldner, Thea Koch, Marcelo Gama de Abreu, Robert Huhle
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-10-01
Schriftenreihe:	Respiratory Research
Schlagworte:	Subject-ventilator asynchrony Ineffective efforts Auto-triggering Double-triggering Large animal model
Online-Zugang:	https://doi.org/10.1186/s12931-024-02984-y
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