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Booster dose of mRNA vaccine augments waning T cell and antibody responses against SARS-CoV-2

A gradual decay in humoral and cellular immune responses over time upon SAR1S-CoV-2 vaccination may cause a lack of protective immunity. We conducted a longitudinal analysis of antibodies, T cells, and monocytes in 25 participants vaccinated with mRNA or ChAdOx1-S up to 12 weeks after the 3rd (boost...

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Principais autores: Feyza Gül Özbay Kurt, Alisa Lepper, Catharina Gerhards, Mathis Roemer, Samantha Lasser, Ihor Arkhypov, Rebekka Bitsch, Peter Bugert, Peter Altevogt, Cécile Gouttefangeas, Michael Neumaier, Jochen Utikal, Viktor Umansky
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-10-01
coleção:Frontiers in Immunology
Assuntos:
SARS-CoV-2
mRNA vaccine
vector vaccine
booster dose
T cell response
antibodies
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1012526/full
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