Aberrant let7a/HMGA2 signaling activity with unique clinical phenotype in JAK2-mutated myeloproliferative neoplasms

High mobility group AT-hook 2 (HMGA2) is an architectural transcription factor that is negatively regulated by let-7 microRNA through binding to it’s 3′-untranslated region. Transgenic mice expressing Hmga2 with a truncation of its 3′-untranslated region has been shown to exhibit a myeloproliferativ...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Chih-Cheng Chen, Jie-Yu You, Jrhau Lung, Cih-En Huang, Yi-Yang Chen, Yu-Wei Leu, Hsing-Ying Ho, Chian-Pei Li, Chang-Hsien Lu, Kuan-Der Lee, Chia-Chen Hsu, Jyh-Pyng Gau
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Ferrata Storti Foundation 2017-03-01
coleção:	Haematologica
Acesso em linha:	https://haematologica.org/article/view/8002
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!