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Impairment of FOS mRNA stabilization following translation arrest in granulocytes from myelodysplastic syndrome patients.

Although quantitative and qualitative granulocyte defects have been described in myelodysplastic syndromes (MDS), the underlying molecular basis of granulocyte dysfunction in MDS is largely unknown. We recently found that FOS mRNA elevation under translation-inhibiting stimuli was significantly smal...

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Principais autores: Xiaomin Feng, Yayoi Shikama, Tsutomu Shichishima, Hideyoshi Noji, Kazuhiko Ikeda, Kazuei Ogawa, Hideo Kimura, Yasuchika Takeishi, Junko Kimura
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3625160?pdf=render
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