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Eco-Friendly, Simple, Fast, and Sensitive UPLC-MS/MS Method for Determination of Pexidartinib in Plasma and Its Application to Metabolic Stability

Pexidartinib is the first drug approved by the U.S. Food and Drug Administration specifically to treat the rare joint tumor tenosynovial giant cell tumor. In the current study, a validated, selective, and sensitive UPLC-MS/MS assay was developed for the quantitative determination of pexidartinib in...

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Uloženo v:
Hlavní autoři: Essam Ezzeldin, Muzaffar Iqbal, Yousif A. Asiri, Gamal A. E. Mostafa, Ahmed Y. A. Sayed
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-01-01
Edice:Molecules
Témata:
UPLC-MS/MS
pexidartinib
tyrosine kinase inhibitor
metabolic stability
gifitinib
On-line přístup:https://www.mdpi.com/1420-3049/27/1/297
Tagy: Přidat tag
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